Web23 mar. 2024 · Chen, C. et al. TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Web15 ian. 2014 · Background: The mammalian target of rapamycin (mTOR) is an important regulator of hematopoietic stem cell (HSC) self-renewal and its overactivation …
NKAP functions as an oncogene and its expression is induced by …
WebmTORC1 plays a role in the differentiation and proliferation of hematopoietic stem cells. Its upregulation has been shown to cause premature aging in hematopoietic stem cells. Conversely, inhibiting mTOR restores and regenerates the hematopoietic stem cell line. Web5 ian. 2024 · These results provide insights into the physiological role of mTOR in mammalian stem cell regulation and implicate a mechanism of evasive resistance in the … shutter screws brown
Differential Reponses of Hematopoietic Stem and Progenitor Cells …
Web12 mar. 2015 · As Associate Professor of Anatomy and Cell Biology at the University of Iowa, my research program continues to focus on understanding the complex mechanisms that contribute to the pathogenesis of ... WebCell separation analysis of B and T lymphocyte differentiation. Cell separation analysis of B and T lymphocyte differentiation Transplant Rev. 1975;25: ... Hematopoietic Stem Cells Immunity, Cellular Mice Mice, Inbred AKR Mice, Inbred C3H ... Web6 aug. 2024 · Liu L, Inoki A, Fan K, Mao F, Shi G, Jin X, et al. ER-associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity. Blood. 2024;136:2975–86. shutters cottage