Ic50 value of cisplatin

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August undefined, 2024

Webb2 nov. 2015 · The IC 50 values of both curcumin and cisplatin in the A549 and H2170 cells were tested on IMR-90 cells to evaluate the toxic effect of curcumin and cisplatin on … WebbIC50 cisplatin concentration (mM) Source publication Lifeguard inhibition of Fas-mediated apoptosis: A possible mechanism for explaining the cisplatin …

miR-1269b Drives Cisplatin Resistance of Human Non-Small Cell …

WebbIt was found that the IC50 value of S. Typhimurium OMVs which caused 50% growth inhibition was 16.7 ... 6Gy) or treated with cisplatin (CIS, 15 mg/kg, i.p.) for induction of nephrotoxicity ... Webb1 apr. 2024 · Multivariate results showed that MMP-High could be used as an independent predictor of the prognosis of SCLC after cisplatin treatment (HR = 0.216, p = 0.00153; … healthy dessert alternatives

Targeted therapy for cisplatin‐resistant lung cancer via …

WebbThe half maximal inhibitory concentration (IC50) values of these cells to cisplatin have been published [26,27,28]. Particularly, OVCAR3CIS are 4.5 times more resistant to cisplatin in comparison to their cisplatin-sensitive counterparts, OVCAR3 cells . 2.2. Webb15 juni 2024 · The IC50 value was inversely proportional to DDP sensitivity. Detection of apoptosis by flow cytometry (FCM) After digestion with 0.25% trypsin (Chreagen, Beijing, China, 121520) and two rinses with PBS, the cells were added with 100 μL of binding buffer to prepare a 1×10 6 cells/mL suspension. Webb0.744770. Filter: 760 entries 1 2 3 ... 31 CSV TAB XLS. The Genomics of Drug Sensitivity in Cancer Project is a collaboration between the Cancer Genome Project at the Wellcome Sanger Institute (UK) and the Center for Molecular Therapeutics, Massachusetts … motorsports playground

PKM2 was upregulated in cisplatin resistant BC cells. (A

Dr. Jan Bandolik – Apotheker – Berg- und Hütten-Apotheke

WebbLncRNA HOTTIP Participates in Cisplatin Resistance of Tumor Cells by Regulating miR-137 Expression in Pancreatic Cancer . Fulltext; Metrics; Get Permission; Cite this … Webb11 apr. 2024 · The values were presented as the mean ± standard deviation ... The drug responses of GC cells to 5-FU and cisplatin cultured in normoxia of 2d dish and 3d-ACS. ... Lin et al., 2024), and overall higher IC50 values, more resistance, and less apoptosis were obtained in 3d-ACS (Figures 4C, D). motorsports plus conway nhWebbWhat Cisplatin Is Used For: Treatment of advanced bladder cancer, metastatic ovarian cancer, and metastatic testicular cancer. Testicular, ovarian, bladder, head and neck, esophageal, small and non-small cell lung, breast, cervical, stomach and prostate cancers. healthy designs chandler

"WebbAnswer to Question: Please calculate and state the EC50, IC50 " - Ic50 value of cisplatin

Ic50 value of cisplatin

WO2024035200A1 - Application of pentafluorite in preparation of …

Webb12 aug. 2009 · IC 50 values of MBIs are time dependent, causing serious problems when aiming at ranking different compounds with respect to their inhibitory potential. As a consequence, most studies and ranking schemes related to MBIs rely on the inhibition constant (K I) and the rate of enzyme inactivation (k inact) rather than on IC 50 values. Webb22 maj 2024 · IC 50 values to cisplatin in the cisplatin-sensitive and resistant HNSCC cells are listed. Cells were treated with increasing doses of cisplatin for 72 h and IC 50 …

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WebbIC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological … WebbThe IC50 values of cisplatin were 22.4 μM and 12.3 μM in HeLa cells; 25.5 μM and 7.7 μM in HepG2 cells; 15.4 μM and 4.9 μM in V79 cells; for 24 h and 48 h, respectively. …

Webb16 feb. 2016 · As presented in Fig. 2, the IC 50 values of cisplatin were 88.89, 13.20 and 9.55 µ M for 24, 48 and 72 h in the A2780 sensitive cell line, respectively. However, the … WebbIC50 values indicated less toxicity of the Schiff base complex on GMSCs compared to cisplatin. Schiff base complex treatment resulted in up-regulation of p53 and Bax genes expression and down-regulation of Bcl2 gene expression in SCCs paralleled with increased protein expression of caspase-3 and Bax and down-regulation of Bcl-2 protein.

Webb20 juli 2024 · The half-maximal inhibitory concentration (IC50) of therapeutic drugs was estimated using the R package pRRophetic, and the differences of IC50 values between the high- and low-risk groups were then compared. 2.8. Tissue samples and real-time quantitative PCR (RT-qPCR) assay WebbImportantly, after treatment with the siRNA, the IC50 value of cisplatin in MCS cells became no longer significantly different from that in ADCs (P=0.2754; Figure 4B). …

Webb11 apr. 2024 · Results: 661 cell lines were divided into three groups according to the IC50 value of cisplatin, and the top 1/3 (220) with a small IC50 value were defined as the …

WebbOverexpressing miR-515-5p markedly reduced cisplatin and 5-Fu IC50 values in HK-1/CDDP and CNE-1/CDDP cells, while IL-25 transfection was sufficient to reverse this phenotype (Figure 4E and F). As such, our data demonstrate that circNRIP1 enhances 5-Fu and cisplatin resistance in NPC cells at least in part via sequestering miR-515-5p … motorsports porscheWebbThe present invention relates to the technical field of drugs, and in particular, to an application of pentafluorite in the preparation of a drug for treating endometrial cancer. Studies of the present invention show that pentafluorite has the effects of inhibiting proliferation, clone formation and migration ability of endometrial cancer ISK and KLE … healthy dessert for easterWebb15 sep. 2024 · The “half maximal inhibitory concentration” (or “IC50”) is a measure of the potency of an agent in inhibiting a specific biological or biochemical function. This quantitative measure indicates how much of a particular agent (inhibitor) is needed to inhibit a given biological process (or component of a process, i.e. an enzyme, cell, cell … motorsports prescott